Granulophysin

Author: wcwk

August undefined, 2024

WebThe immunological crossreactivity between the two granule‐specific membrane glycoproteins, synaptophysin and granulophysin, was studied using a series of … WebGranulophysin (CD63) is a protein in the tetraspanin group and is found in, among others, the dense granules and the α-granules of platelets [139,140], as well as the azurophilic granules of ...

Megakaryocyte dense granule components are sorted in …

WebGRANULOPHYSIN HGNC Approved Gene Symbol: CD63 Cytogenetic location: 12q13.2 Genomic coordinates (GRCh38): 12:55,723,535-55,730,041 (from NCBI) TEXT Cloning … WebHuman CD63 antigen, also referred to as Granulophysin, Lysomal-associated membrane protein 3 (LAMP-3), Tetraspanin-30, and Ocular melanoma-associated antigen, is a membrane bound protein encoded by the gene CD63. CD63 belongs to a group of proteins known as the tetraspanin family, which are characterized by the presence of four … shannon sheds

PE-Cy™7 Mouse Anti-Human CD63 - BD Biosciences

Webgp55; granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3); Mast cell antigen AD1; Melanoma-associated antigen ME491; MLA1; NGA; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin-30; TSPAN30. Positive Control. SK-MEL-28, HL60, THP-1 or NIH/3T3 cells. Human spleen or lymphoma tissue (IHC). WebTarget Information. CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation … WebView application images and datasheets for 1333 anti Granulophysin Antibody antibodies from 38 leading antibody suppliers, plus reviews and the top related antibodies shannon sherlock covington la

CD63 Protein Overview: Sequence, Structure, Function and …

(PDF) The protein CD63 is in platelet dense granules, is

WebNormal human peripheral blood cells were stained with CD193 (CCR3) Monoclonal Antibody, PE (Product # 12-1939-42) and IgE Monoclonal Antibody, FITC (Product # 11-6986-42) only (blue histogram), or stained with CD63 Monoclonal Antibody, NovaFluor Red 700 (Product # H074T03R03) (purple histogram). WebAbout This Kit. Human CD63 quantitates human CD63 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD63. CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. shannon sherfey hickory ncWebThese characteristics are similar to an individual with Hermansky-Pudlak syndrome and are consistent with a platelet dense granule deficiency. In contrast, immunofluorescence studies using an antibody against the dense granule membrane protein granulophysin suggested that both sisters had numbers of granules within the normal range. shannon sherman mississippi arrest

"WebJul 1, 1994 · Granulophysin, a protein described in platelet dense granule membranes, has been shown to be similar or identical to CD63, a … " - Granulophysin

Granulophysin

Frozen-thin section with immunogold preparation of a portion of a ...

WebPE-Cy7 is a tandem fluorochrome composed of R-phycoerythrin (PE), which is excited by 488-nm light and serves as an energy donor, coupled to the cyanine dye Cy7, which acts as an energy acceptor and fluoresces maximally at 780 nm. PE-Cy7 tandem fluorochrome emission is collected in a detector for fluorescence wavelengths of 750 nm and higher. WebSep 1, 1992 · Recently the platelet protein granulophysin, specific to the membrane of the DG, has been described and defined through the use of monoclonal antibodies …

Did you know?

WebUniProt Accession Number of Target Protein: P08962 Alternative Name(s) of Target: Granulophysin; LAMP-3; ME491; MLA1; OMA81H; TSPAN30; LAMP3 Immunogen: Human monocytes. Specificity: This antibody binds to CD63 on monocytes and activated neutrophils. Application Notes: This antibody binds to CD63, a membrane-spanning … WebGenerally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. Shipping. This product is provided as lyophilized powder which is shipped with ice packs.

WebAnti-CD63 (LAMP3), clone ME491, Cat. No. MABF2159, is a mouse monoclonal antibody that detects CD63 antigen and has been tested for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), and Western Blotting. Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot … WebNational Center for Biotechnology Information

WebJun 1, 1997 · Granulophysin labels the dense granule membrane (D) but not the α-granules (A). Gp Ib is found essentially along the plasma membrane (pm). The OCS and some α-granules (A) are occasionaly labeled. It also double-labels the dense granule membrane (D) identified by the presence of granulophysin. (Original magnification × … WebNaked mole-rats are long-lived animals that show unusual resistance to hypoxia, cancer and ageing. Protein deimination is an irreversible post-translational modification caused by the peptidylarginine deiminase (PAD) family of enzymes, which convert arginine into citrulline in target proteins. Protein deimination can cause structural and functional protein changes, …

WebJun 15, 2000 · It can only be identified by GPIb-specific expression on its plasma membrane (pm). Granulophysin labels the membrane of vacuolar structures, which can be …

Webnoun. gran· u· lo· poi· e· sis - (ˌ)lō-ˌpȯi-ˈē-səs. plural granulopoieses -ˌsēz. : the formation of blood granulocytes typically in the bone marrow. called also granulocytopoiesis. … shannon shelley sparta tnWebApr 1, 1994 · In lysates prepared from prostasomes, a broad band of 32 to 37 kd was detected by Western blotting. Conclusion This report defines granulophysin as a constituent membrane molecule of prostasomes that may serve as a useful marker in elucidation of prostasome function. Key Words Human seminal plasma prostasomes … pomona dept of motor vehiclesWebCD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, Lysosome integral membrane protein 1, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, CD63_HUMAN shannon sheridanWebNov 6, 2024 · Level of granulophysin on the platelet surface. A, 5‐ HT /catecholamine‐treated or ‐untreated platelets were evaluated by measuring the level of granulophysin, a surrogate marker for dense‐granule … pomona earthquake todayWebDescription: Homo sapiens CD63 molecule (CD63), transcript variant 3, mRNA. (from RefSeq NM_001257389) RefSeq Summary (NM_001257389): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the … pomona earth dayWebBrand: BD Pharmingen™ Alternative Name: LAMP-3; ME491; MLA-1; Granulophysin; Ptgr40; NGA; gp55 Reactivity: Human (QC Testing), Rhesus, Cynomolgus, Baboon … pomona drain cleaningWebLesley R. de Armas, Eckhard R. Podack, in Natural Killer Cells, 2010 Granulysin. Granulysin is a member of the saposin-like protein (SAPLIP) family that is also a component of … pomona earthquake