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Breast cancer resistance protein 意味

WebBreast cancer resistance protein (BCRP) was identified 7 years ago as the most recent member of ABC drug efflux membrane transporters. It is a 655 amino acid peptide with … WebDec 2, 2024 · 三个皮匠报告网每日会更新大量报告,包括行业研究报告、市场调研报告、行业分析报告、外文报告、会议报告、招股书、白皮书、世界500强企业分析报告以及券商报告等内容的更新,通过行业分析栏目,大家可以快速找到各大行业分析研究报告等内容。

ABCG2 - Wikipedia

WebApr 1, 2002 · Abstract. Inhibitors of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter are of interest as chemosensitizers for clinical drug resistance, for improving the pharmacokinetics of substrate chemotherapeutic drugs, and in functional assays of BCRP activity for tailoring chemotherapy. The fungal toxin fumitremorgin C … WebSep 1, 2004 · Gefitinib inhibits the transporter function of BCRP and reverses B CRP-mediated drug resistance both in vitro and in vivo, and suggests that gefit inib may overcome BCRp- mediated drug resistance by inhibiting the pump function ofBCRP. Breast cancer resistance protein (BCRP) is an ATP binding cassette transporter that confers … cama hello kitty https://theposeson.com

クレストール(fluvastatin)とフェブリク(febuxostat)の併用 …

WebATP binding cassette (ABC)-containing drug efflux transporters play important roles in regulating intracellular drug concentrations that determine cell sensitivity to chemotherapeutic agents. Of particular relevance to … This protein is a member of the White subfamily. Alternatively referred to as the breast cancer resistance protein (BCRP), this protein functions as a xenobiotic transporter which may play a role in multi-drug resistance to chemotherapeutic agents including mitoxantrone and camptothecin analogues. See more ATP-binding cassette super-family G member 2 is a protein that in humans is encoded by the ABCG2 gene. ABCG2 has also been designated as CDw338 (cluster of differentiation w338). ABCG2 is a translocation … See more It is inhibited by some calcium channel blockers such as amlodipine, felodipine and nifedipine. The fungal toxin fumitremorgin C (FTC) inhibits the protein but has neurotoxic side … See more • ABCG2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human ABCG2 genome location and ABCG2 gene details page in the See more The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. The active transport of chemicals … See more • ATP-binding cassette transporter See more • Hazai E, Bikádi Z (April 2008). "Homology modeling of breast cancer resistance protein (ABCG2)". Journal of Structural Biology. 162 (1): 63–74. doi: • Abbott BL (January 2006). … See more cama hemnes ikea montaje

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Category:BCAR3 BCAR3 adaptor protein, NSP family member [ (human)]

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Breast cancer resistance protein 意味

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Web4 hours ago · CU Boulder researchers have discovered a protein’s crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that … WebOct 14, 2015 · ABCG2/breast cancer resistance protein (BCRP) is a member of the adenosine triphosphate-binding cassette (ABC) transporter protein family. It is referred …

Breast cancer resistance protein 意味

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WebThe recent demonstration that addiction-relevant neuronal ensembles defined by known master transcription factors and their connectome is networked throughout WebJun 12, 2024 · Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have been developed, but most of them fail in clinical trials due to severely adverse effects. Recently, certain natural products have been reported to overcome …

Webbreast cancer resistance protein - 1000万語の英語の意味を収録!Weblio英和・和英辞書 ... 「breast cancer resistance protein」の意味に関連した用語 ... WebApr 1, 2002 · Abstract. Purpose: The breast cancer resistance protein (BCRP) is involved in in vitro multidrug resistance and was first identified in the breast cancer cell line …

WebBreast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene … WebFeb 1, 2003 · Abstract. Purpose: The aim of this study was to investigate whether expression of particular drug resistance genes in primary operable breast cancer correlates with response to first-line chemotherapy in advanced disease.Experimental Design: We determined mRNA levels of BCRP, LRP, MRP1, MRP2, and MDR1 in 59 …

Web日本レーザー医学会誌. 癌薬物療法において薬剤耐性の出現は大きな障壁の1つである.特に薬剤排出ポンプによる薬剤の細胞外への排出に関しては,様々な種類のトランス …

WebApr 1, 2002 · Abstract. Purpose: The breast cancer resistance protein (BCRP) is involved in in vitro multidrug resistance and was first identified in the breast cancer cell line MCF7/AdrVp. The aim of this study was to investigate the role of BCRP in resistance of breast cancer to anthracycline treatment.Experimental Design:BCRP mRNA was … cama nissan nv200WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. camaf joinWebFeb 1, 2012 · A synopsis of the impact of BCRP-mediated MDR in cancer cells, and the molecular mechanisms of acquired MDR currently postulated in a variety of human cancers are presented. Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2 (ABCG2) is an ATP-binding cassette (ABC) transporter identified as a … 好き嫌いWebMar 5, 2024 · Introduction. Multidrug resistance (MDR) accounts for chemotherapeutic resistance in cancer cells ().Three major proteins namely P-glycoprotein (P-gp, also referred to as MDR1), MDR … camafeo joias onlineWebBreast cancer resistance protein (BCRP) is a half-molecule ATP-binding cassette transporter that forms a functional homodimer and pumps out various anticancer agents, such as 7-ethyl-10-hydroxycamptothecin, topotecan, mitoxantrone and flavopiridol, from cells. Estrogens, such as estrone and 17β-estradiol, have been found to restore drug ... cama queen tok stokWeb1 day ago · Scientists at VCU Massey Cancer Center discovered that the deletion of a specific protein creates a hostile environment for tumor cells and significantly subdues … 好き嫌い 小川WebBCRP was originally identified as a multidrug resistance protein in cancer cells. It is expressed in mammary tissue, testis, placenta, and the gastrointestinal tract, kidney, … cama rosen style 6